Discussion
Loading...

Stefan Rödiger

  • Following
  • Followers
  • Send a message
  • Flag Stefan Rödiger
  • Block
  • Copy link
  • Following
  • Followers
  • Send a message
  • Flag Stefan Rödiger
  • Block
Follow

Stefan Rödiger

@pangolin@sandbox.openscience.network

Prof. & Researcher focused on #Bioanalytics, #Bioinformatics, #Pharma, Human #diagnostics (#LiquidBiopsy) and a bit #Forensics

Website
www.b-tu.de/en/fg-multiparameterdiagnostik/rg-roediger
Other profiles
RoedigerRG

RoedigerRG

@RoedigerRG@social.anoxinon.de
0000-0002-1441-6512
Current Institution: Brandenburg University of Technology Cottbus-Senftenberg
Past institutions: University of Potsdam , University of Surrey , Faculty of Public Health , Brandenburg University of Technology Cottbus-Senftenberg , Frankfurt University of Applied Sciences , Technical University of Munich , Charité - Universitätsmedizin Berlin
Stefan Rödiger
Stefan Rödiger
@pangolin  ·  activity timestamp 10 years ago

chipPCR: an R package to pre-process raw data of amplification curves

  • Copy link
  • Flag this media
  • Block
Stefan Rödiger
Stefan Rödiger
@pangolin  ·  activity timestamp 10 years ago
De Gruyter Brill

Clinical Chemistry and Laboratory Medicine (CCLM)

Objective Clinical Chemistry and Laboratory Medicine ( CCLM ) publishes articles on novel teaching and training methods applicable to laboratory medicine. It is focused on basic and applied research and cutting-edge clinical laboratory medicine. CCLM is one of the leading international journals in the field of clinical laboratory sciences and drives progress in the field. CCLM is led by a multi-institutional editorial board. All contributions submitted for publication in CCLM are single-blind peer reviewed by at least two experts in the field. CCLM is led by a multi-institutional editorial board. It is issued monthly , both in print and electronically. Letters to the Editor and Congress Abstracts are published online only. CCLM is the official journal of the European Federation of Clinical Chemistry and Laboratory Medicine (EFLM) . Topics clinical biochemistry clinical genomics and molecular biology clinical haematology and coagulation clinical immunology and autoimmunity clinical microbiology drug monitoring and analysis evaluation of diagnostic biomarkers disease-oriented topics (cardiovascular disease, cancer diagnostics, diabetes) new reagents, instrumentation and technologies new methodologies reference materials and methods reference values and decision limits quality and safety in laboratory medicine translational laboratory medicine clinical metrology Article formats Research Articles, Reviews, Mini Reviews and Opinion Papers on all aspects of clinical chemistry and laboratory medicine, Guidelines and Recommendations, Point/Counterpoint Articles, Letters to the Editor, Editorials For EFLM Academy Members To take advantage of all the opportunities offered to members of the EFLM Academy, please access your personal area in the EFLM Academy at the link https://academy.eflm.eu/secretariat/login (if you do not remember your login details, you can use the option FORGOT PASSWORD). Click on the section “International Journals” on the left-hand side where you find CCLM as the first listed journal.
  • Copy link
  • Flag this media
  • Block
Stefan Rödiger
Stefan Rödiger
@pangolin  ·  activity timestamp 10 years ago

Unspecified server error

  • Copy link
  • Flag this media
  • Block
Stefan Rödiger
Stefan Rödiger
@pangolin  ·  activity timestamp 10 years ago
SpringerLink

Simultaneous detection of celiac disease-specific IgA antibodies and total IgA - Autoimmunity Highlights

Purpose Celiac disease (CD) serology requires analysis of tissue transglutaminase type-2 (TG2autoAbs), deamidated gliadin (DGAbs), and as reference endomysial autoantibodies (EmA). Total IgA assessment helps to determine IgA-deficient CD patients. The novel multiplex indirect immunofluorescence (IIF) technique CytoBead was used to develop the first quantitative one-step serological CD assay comprising both simultaneous IgA autoAb and total IgA testing. Methods CytoBead CeliAK detecting TG2autoAb, DGAb, EmA, and simultaneously total IgA uses fluorescent microparticles for antigen and antibody immobilization along with monkey-esophagus tissue sections on glass slides. The assay was interpreted visually by classical fluorescent microscopy and digital IIF using AKLIDES®. Overall, 380 samples (155 CD patients, 5 with IgA deficiency, 68 with cystic fibrosis, 59 with eye disease, 93 blood donors) were run for performance analysis. Data were compared with classical IgA autoAb analysis by ELISA and IIF. Results Comparing CD-specific IgA autoAb testing by CytoBead with classical IIF and ELISA, very good agreements for EmA, TG2autoAb, and DGAb were determined (Cohen’s κ = 0.98, 0.96, 0.85, respectively). The difference between multiplex and single testing revealed a significant difference for TG2autoAb testing only (McNemar, p = 0.0078). Four CD patients and 4 controls demonstrated TG2autoAb positivity by ELISA but were negative by CytoBead. Further, 140/155 (90.9 %) CD patients demonstrated TG2autoAb levels above ten times the upper normal and all five IgA-deficient samples IgA levels <0.2 g/L by CytoBead. Conclusions The novel multiplex CytoBead CeliAK enables simultaneous CD-specific autoAb and IgA deficiency analyses comparable with classical testing by single-parameter assays. Thus, comprehensive CD serology by CytoBead can alleviate the workload in routine laboratories.
  • Copy link
  • Flag this media
  • Block
  • Most Recent Publication

    Cannabidiol does not cause DNA double-strand breaks in a human liver-derived cel...

    Journal of Cannabis Research • 2025
    Open Access
    View
  • Author Topics
    Molecular Biology Techniques and Applications 16
    Advanced Biosensing Techniques and Applications 16
    Advanced biosensing and bioanalysis techniques 12
    Escherichia coli research studies 9
    Biosensors and Analytical Detection 8
  • Publication Types
    Article 69
    Preprint 6
    Review 6
    Dataset 5
    Letter 1
    Peer-review 1
  • Trending topics
    • #datascience
      1 activity
    • #fediverse
      1 activity
    • #biology
      1 activity
    • #science
      1 activity
    • #mastodon
      1 activity
    • #socialmedia
      1 activity
    • #bonfire
      1 activity
    • #socialweb
      1 activity
    • #scientificillustration
      1 activity
    • #digitalcommunity
      1 activity
  • Admins
    Open Science Network

    Open Science Network

    @admin
    Mayel

    Mayel

    @mayel

Open Science

We are a network of scientists, developers and organizations building the next generation of digital spaces for open science.

Open Science: About · Code of conduct · Privacy · Users · Instances
Bonfire open science · 1.0.1 no JS en
Manual federation enabled
Log in
  • Explore
  • About
  • Members
  • Code of Conduct